Succinyl CoA catalytically inabadilishwa kuwa succinate (Mtini. 13.9), CoA, na GTP kwa kutumia kimeng'enya cha succinyl CoA synthetase succinyl CoA synthetase Succinyl coenzyme A synthetase (SCS, pia inajulikana as succinyl-CoA synthetase au succinate thiokinase au succinate-CoA ligase) ni enzyme ambayo huchochea athari inayoweza kutenduliwa ya succinyl-CoA ili kunyonya. https://sw.wikipedia.org › Succinyl_coenzyme_A_synthetase
Succinyl coenzyme A synthetase - Wikipedia
. Succinyl CoA synthetase (EC 6.2. 1.5) huchochea hidrolisisi ya succinyl CoA hadi suksini na ATP na hivyo kuwakilisha sehemu ya ajabu ya kiwango cha fosphorylation ya substrate [2, 18].
Ni nini huzalishwa succinyl-CoA inapobadilishwa kuwa succiny?
Kubadilika kwa succinyl CoA kuwa asidi succinic kunahusisha kuondolewa kwa kimeng'enya cha CoA na hatua hiyo hutoa nishati katika umbo la GTP. Hatua hii huzalisha ATP katika mimea.
Succinyl-CoA inapobadilishwa kuwa succiny Je, ni vitu gani viwili vinavyozalishwa?
Succinyl CoA hubadilishwa kuwa succinyl katika mmenyuko unaochochewa na kimeng'enya cha succinyl-CoA synthetase. Maoni haya hubadilisha fosfati isokaboni, Pi, na GDP kuwa GTP na pia hutoa kikundi cha SH-CoA. Hatua ya 6. Succinate inabadilishwa kuwa fumarate katika mmenyuko unaochochewa na succinate dehydrogenase.
Je succinyl-CoA inaweza kunyonya oxidation?
(6)Uoksidishaji wa Succinate hadi Fumarate Succinyl-CoA imetiwa oksidi na kufumarate na flavoprotein succinate dehydrogenase (kulia).
Succinyl-CoA inabadilishwa vipi kuwa propionate?
Kwa hivyo, propionyl-CoA inatokana na ukataboli wa lipids na protini. Katika cheu, propionate kwa kiasi kikubwa inatokana na uchachushaji wa bakteria kwenye rumen. Propionyl-CoA inabadilishwa kuwa succinyl-CoA, ambayo hutiwa oksidi au kubadilishwa kuwa glukosi kwa njia ya oxaloacetate na pyruvate (gluconeogenesis; Sura ya 15).